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Description
When neurological symptoms are present, more intensive treatment is required: 1 mg hydroxocobalamin on alternate days until no further improvement occurs, followed by maintenance therapy every two months
Metformin-related vitamin B12 deficiency occurs as metformin causes reduced vitamin B12 absorption by interfering with the vitamin B12-intrinsic factor complex
Vitamin B12 metabolism: a network of multi-protein mediated processes
That coordination bond is pH-sensitive, temperature-sensitive, and oxygen-sensitive
