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Reported data show clinically meaningful HbA1c reductions and weight loss exceeding semaglutide monotherapy in the same population, supporting continued Phase 3 investigation

In contrast, adult-onset patients exhibited milder cognitive impairments, likely due to more stable brain energy metabolism and blood flow regulation during glucose fluctuations, as key stages of brain development were already complete 37

Vegetarians and Vegans: Since vitamin B12 is primarily found in animal-based foods, individuals who follow vegetarian or vegan diets may not get adequate levels through food alone

[DOI] [PMC free article] [PubMed] [Google Scholar] 225.Hong, W., Mo, F., Zhang, Z., Huang, M