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A study using a three-dimensional tumour sphere model combined with CRISPR-Cas9 screening reported that Nrf2 overactivation was essential for lung tumour proliferation and survival, whereas silencing of Nrf2 predisposed spherical cells to ferroptosis, which was also consistent with clinical observations [77]

Despite these promising findings, several limitations and challenges remain in current research

Additionally, optimizing ligand specificity and transport efficiently remains critical for maximizing therapeutic outcomes while minimizing systemic exposure

As discussed, it also supports the activity of Vitamin C and Vitamin E, which protects the cells from inflammatory attack and, thus, increases each cell's longevity, leading to better workouts