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A 1997 meta-analysis of 14 RCTs concluded the benefits of improved hemodynamic cardiac parameters such as stroke volume, cardiac output, ejection fraction, cardiac index, and end-diastolic volume index [125]

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In another study, the novel small lipotripeptides DICAMs, which are non-cationic fatty amine-tripeptide conjugates, effectively prevented the formation of biofilms by breaking down biofilms and eliminating the biofilm-affixed bacteria [91]

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Cefamandolea review of chemistry and microbiology

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