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Even at high oral dosages, fucoidan derived from Undaria pinnatifida and Laminaria japonica has been shown to be safe in animal models, and human clinical investigations have also shown that it has no harmful effects on health (Chung et al., 2010
Sowa ST

Yan X, Song J, Zhang Y, Yang M, Deng Z, Gao B, Zhu Y, Xu C, Ding C, Zhang M, et al

Store-operated Ca 2+ signaling in dendritic cells occurs independently of STIM1
