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[DOI] [PubMed] [Google Scholar] 20.Yerushalmi R, Woods R, Ravdin PM, Hayes MM, Gelmon KA

Macrophage migration inhibitory factor limits renal inflammation and fibrosis by counteracting tubular cell cycle arrest

Thus, physiological conditions that increase catecholamines and glucagon concentrations can activate the PGC-1 pathway via elevated intracellular cAMP levels
