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pIgR and PECAM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion

In vivo rodent models have explored the pharmacokinetics and tissue distribution of Proxofim, examining whether the protease-resistant DRI backbone achieves sufficient systemic exposure and tissue penetration

[DOI] [PMC free article] [PubMed] [Google Scholar] 242.The Human Metabolome Database (HMDB) [(accessed on 1 September 2023)]

This strengthens the role of lithium in maintaining synaptic function by GSK-3 and IMPA-dependent mechanisms (see Figure 1B)
