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D., & Watowich, S
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In fat cells, 5-amino-1MQ lowered the NNMT byproduct 1-methylnicotinamide (EC50 near 2.3 micromolar) and cut fat storage, without disturbing the other enzymes in the NAD+ salvage pathway
Badenhorst 2016 measured wrinkle volume reductions up to 55.8% and depth reductions of 32.8% over 12 weeks of topical use
