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Butyrate acts as a HDAC inhibitor in immune cells, suppressing the expression of pro-inflammatory cytokines (TNF-, IL-6) and enhancing the integrity of epithelial tight junctions

Aging CellIdentification of a small molecule SR9009 that activates NRF2 to counteract cellular senescence

The researchers examined records from 1,796 acute heart attack patients seen in a large healthcare system over six years, including 126 who received low-dose colchicine prescriptions, but found no relationship between colchicine and combined cardiovascular events risk
