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"Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4"

Plasma membrane localization of G-CSFR was observed in control cells, whereas internalization of G-CSFR was detected in -toxin-treated cells in the presence and absence of G-CSF (Fig

It is well known that during the oxidative stress caused by the exhaustive exercise, the levels of biochemical indices, e.g., lactate dehydrogenase (LDH) and superoxide dismutase (SOD) involved in the elimination of metabolites generated from fatigue, are significantly altered, ultimately alleviating the EIF, while the regulatory mechanisms underlying the involvement of LDH and SOD in the response to EIF are extensively explored (Armstrong et al., 1983