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It had long been hypothesized that antioxidants might be able to protect against cancer because they neutralize reactive oxygen species (ROS) that can damage DNA

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10.1021/acsomega.9b02003 105 ZhangL.ChangJ.ZhaoY.XuH.WangT.LiQ.et al (2018)

One study demonstrated that gluconeogenic intermediates, such as pyruvate, malate, and phosphoenolpyruvate (PEP), are neuroprotective against MPP + toxicity