glutathione deficiency dna a1298c One-Carbon Metabolism: Pulling the Strings behind Aging and Neurodegeneration MTHFR (methylenetetrahydrofolate reductase: EC 1.5.1.20)
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MtDNA depletion causes apoptosis in granulosa cells (107)

The anti-proliferative effect was found to be due to the arrest of cells in S/G2-M phase of cell cycle, with increased fraction of apoptotic cells

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