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The chronic activation of the type I IFN pathway is a hallmark of SLE and contributes to the dysregulation of immune responses in this disease [132]

Experimental studies have utilized diverse animal models including transgenic mice (APP/PS1, 5FAD), senescence-accelerated mice (SAMP8), and even Drosophila melanogaster to explore these mechanisms

Human Reproductive Biology (Academic Press, 2013)
10.1016/j.brainres.2007.05.028 155 LeyJ
