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VEGFC binding to VEGFR3 induces receptor dimerization, autophosphorylation, and internalization and activates PI3K/AKT and MAPK/ERK signaling pathways important for lymphangiogenesis [81] (Figure 2a)

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*Correspondence: Heidi Noels, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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10.1007/978-3-540-79885-9_7 Handb

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Puig, Raquel Parada

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