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Pasello et al reported that this agent effectively reversed cisplatin resistance in osteosarcoma, alluding toward potentially improved clinical outcomes when using a combination of NBDHEX and cisplatin
Agrawal KK, Murti Y, Tangeretin
Science 347 , 13741377 (2015)
Regarding the few pathways where the result seems incongruous, when analyzing their topology, it is clear that their activation by B12 is potentially beneficial to the patient
