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Rosenwasser, 2001), and there is recent evidence for decreased expression of several circadian clock genes (Huang et al., 2010a) as well as a polymorphism in one of the genes ( Per3 ) that is associated with insomnia severity in alcohol-dependent subjects (Brower et al., 2012)

Most people have mild symptoms

In this case, they were eating a standard chow control diet, called "Teklad 2018": Ingredients (in descending order of inclusion): Ground wheat, ground corn, wheat middlings, dehulled soybean meal, corn gluten meal, soybean oil, calcium carbonate, dicalcium phosphate, brewers dried yeast, iodized salt, L-lysine, DL-methionine, choline chloride, kaolin, magnesium oxide, vitamin E acetate, menadione sodium bisulfite complex (source of vitamin K activity), manganous oxide, ferrous sulfate, zinc oxide, niacin, calcium pantothenate, copper sulfate, pyridoxine hydrochloride, riboflavin, thiamin mononitrate, vitamin A acetate, calcium iodate, vitamin B12 supplement, folic acid, biotin, vitamin D3 supplement, cobalt carbonate

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