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Eye Problems and Vision Loss: Bone and Tooth Deformities: Skin & Hair Deterioration: acne, dry or bumpy skin patches (usually on the face, elbows or knees), phrynoderma (toad skin), loss of skin elasticity, excessive fine lines/wrinkles, poor wound healing, eczema, hyperpigmentation of the skin (melasma, dark patches over elbows or knees), alopecia (hair loss), enlarged hair follicles, dry, brittle hair ( due to inadequate sebum production )4142434445 Hormonal Imbalances: hypothyroidism, goitre, high TSH, infertility, low progesterone, low testosterone, low DHT, high cholesterol ( vitamin A helps convert cholesterol to sex hormones, so in a deficiency the conversion is impaired ), miscarriages, poor sperm quality, all sorts of birth defects ( when the mother is retinol deficient )46 Immune Dysfunction: getting sick easily, frequent respiratory, urinary, gastrointestinal and skin infections, autoimmunity, infections that take longer to resolve and are more severe, chronic inflammation ( vitamin D cannot exert its anti-infective, anti-autoimmunity effects when vitamin A is deficient