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These cells communicate with neurons and each other using chemical mediators such as nitric oxide, ATP, neurotransmitters (i.e., glutamate, substance P), ions (K + , Ca 2+ ), and immune-mediated cytokines (e.g., TNF, IL-1)

Glutathione is synthesised in the cytosol in two steps (Figure 1)

Current protocols recommend treating patients with an initial dose of 150 mg/kg NAC, infused over a period of an hour, upon hospitalization, followed by decreasing amounts of NAC infused over the next 20 hours [1]

Allerdings kann Glutathion durch sein hohes antioxidatives Potenzial die Wirkung bestimmter Chemotherapien vermindern