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Decades of endocrine research had localized much of the lipolytic activity to the C-terminal portion of the molecule

This impairment of DNA synthesis affects the rapidly dividing cells of the bone marrow earlier than other cells, resulting in the production of large, immature, hemoglobin-poor red blood cells (macrocytosis), as well as effects on white blood cells, including abnormal (hypersegmented) neutrophils and reduced overall cell counts (pancytopenia)

These peptide molecules communicate directly with the cells

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