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MT1 appears to be the top option for researchers looking to investigate the potential of melanocortin agonists for [5, 9, 10, 16]: Sunless tanning Reducing the risk of sunburn Increasing tolerance to UV/sunlight Reducing inflammation That is because MT1 has considerably higher selectivity towards MC1R, whose activation is the primary factor that mediates the aforementioned effects

This suggests that targeting of CPT1B may have potential for therapy of enzalutamide resistance [154]