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Eur Rev Med Pharmacol Sci 25(6):28022807 Zhang Q, Ju Y, Ma Y, Wang T (2018) N-acetylcysteine improves oxidative stress and inflammatory response in patients with community acquired pneumonia: a randomized controlled trial

RESULTS GHK-Cu decreased ROS production and improved SOD activity in LPS-induced RAW 264.7 cells activation According to a previous study, GHK-Cu can increase the level of antioxidant enzymes and SOD activity, supposedly by supplying copper, which is necessary for its function [23]

As individuals age, mitochondrial dysfunction becomes increasingly prevalent, contributing to age-related decline in various tissues and organs
The loss of mitochondrial and cytosolic aconitase activities in the muscle samples of patients with ISCU deficiency is consistent with previous studies of cells depleted of ISCU by siRNA-mediated silencing [23]
