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While EAE models have offered valuable insight into adaptive immune responses, demyelination, and axonal damage in MS, they fall short in replicating the full spectrum of human MS pathology, particularly the disease's onset and heterogeneity (Figure 5)

Fagniart et al., 2016)

Pharmaceutical preparations of vitamin B 12 may be given by intramuscular injection

Their interaction can result in damage of cellular components, causing modifications and altered functioning of bio-molecules such as proteins, DNA and others [112,126]
