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It sustains adequate redox cell signaling since a physiologic level of oxidative stress is fundamental for controlling life processes via redox signaling, but excessive oxidation causes cell and tissue damage

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Consistently, NMR analysis revealed elevated levels of glutamine and serine, accompanied by decreased concentrations of the glutamic acid precursor -ketoglutarate in PD patients, while UPLC/MS analysis indicated a reduction in serum glutamic acid levels (Figs

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