does quercetin increase glutathione New perspectives on the therapeutic potential of in non-communicable diseases: Targeting Nrf2 to counteract oxidative stress and inflammation Exploring the mechanistic pathways of

The documented mechanisms are: VEGF stimulation in dermal fibroblasts that supports the microvascular network feeding the follicle, collagen and glycosaminoglycan synthesis at the follicular basement membrane, anti-inflammatory signaling that calms the chronic micro-inflammation associated with androgenetic alopecia, and direct follicular signaling that extends the anagen growth phase

doi: 10.1016/j.clnu.2020.06.015

January 2022

For hair specifically, the relevant subset of these pathways translates into improved follicle environment, reduced oxidative damage to dermal papilla cells, and a calmer inflammatory state three of the four root causes of androgenetic alopecia, addressed simultaneously by a single molecule