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Description
This is the central regulatory problem that full FDA approval would need to solve and it is the reason PCAC reviews for peptides like BPC-157 often hinge on available safety data rather than efficacy evidence from controlled human studies

If the increased demand is not met by the increased thiamine supply, a state of TD may easily follow, first in enterocytes, and after some period at the level of organism, most often manifested as Wernicke encephalopathy (145147)

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Malaguarnera M, Vacante M, Motta M, et al
