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The PIKFYVe encoded enzyme is capable of phosphorylating PtdIns to generate PtdIns-5-P and phosphorylating phosphatidylinositol-3-phosphate (PtdIns-3-P) to generate phosphatidylinositol-3,5-bisphosphate (PtdIns-3,5-P 2

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13 Duration of Therapy: Treatment duration is based on many factors, such as whether the patient is treatment-nave, the extent of liver damage, and the patients response to treatment
