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Case Analysis of Disulfide Bond Identification of the Thiol Isomerase-binding Peptide, Mastoparan, as a Novel Inhibitor of Shear-induced Transforming Growth Factor 1 (TGF-1) Activation Journal: Journal of Biological Chemistry Published: 2013 Background Transforming Growth Factor 1 (TGF-1) is a disulfide-bonded homodimeric cytokine secreted in an inactive large latent complex (LLC) by platelets and other cells