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The DNA methylation clock is a recognized biomarker of aging, and -KG serves as an essential cosubstrate for histone demethylases of the Jumonji C domain-containing family (JMJDs) and for DNA demethylases of the ten-eleven translocation (TET) enzyme family [126]

This FAO shift increased the activity of immunosuppressive enzymes and promoted the generation of regulatory T cells, leading to tumor-mediated immune tolerance

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Tambin permitira aumentar la masa muscular y de reducir la fatiga fsica y mental , como lo demuestran estudios realizados en adultos