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Seeking lower patient burden, Biogen tested a pegylated IFN -1a, which retains similar pharmacodynamic activity to IFN -1a, but its altered pharmacokinetic properties allows less frequent administration
The entire procedure was carried out on ice to preserve protein activity and stability
A further limitation of this study is that it was powered to detect only moderate-to-large differences in CEdG levels and chromatin texture between tumor and normal tissues
Particulate matter floating in solution suggests contamination or precipitation of degradation products
