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575 Similarly, the loss of mitochondrial complex I leads to a decrease in the ratio of NAD + /NADH and can inhibit the activity of Sirt3, thereby enhancing the protein acetylation and mPTP sensitivity

The weight loss curves had not plateaued at week 26, suggesting that longer treatment periods would yield even greater reductions

Prosapip1-dependent synaptic adaptations in the nucleus accumbens drive alcohol intake, seeking, and reward

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