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Gut epithelial TSC1/mTOR controls RIPK3-dependent necroptosis in intestinal inflammation and cancer

The hyperactivity of HPA axis is not the etiological factor that triggers BD, but undoubtable, it contributes to modify clinical presentations of BD and influence the genetic and environmental basic interaction in BD etiopathogenesis [47]

5.4 Western diet The dietary structure of western diet pattern represented by western developed countries is characterized by high energy food intake, high protein, saturated fat, refined cereals, sugar, alcohol and salt, and low intake of omega-3 fatty acids, fruits and vegetables, thus has the diet pattern of three highs of high calories, high fat and high protein

It also increases the oxidation of fatty acids for example, raising levels of carnitine shuttle proteins and -oxidation intermediates in cells which means more fats are transported into mitochondria and used for energy instead of accumulating