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AMPK-related signalling pathway Reports have confirmed that adenosine 5-monophosphate (AMP)-activated protein kinase (AMPK) plays a crucial role in regulating cellular energy metabolism homeostasis

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Manipulation of intracellular GSH pools by supplementation with GSH precursors was found to block induction of JNK activity by methylating agents [26] Similarly p53 function has been reported to be redox sensitive, primarily through in vitro modification of its cysteine residues [27]