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Description
It contributes to increased levels of glutathione , one of the most important endogenous antioxidants
Glutathione peroxidase 4 (GPX4) uses reduced glutathione as a substrate to reduce oxidized lipids to normal lipids, preventing the accumulation of peroxides, and thus inhibiting ferroptosis (20)
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It is characterized by progressive skeletal muscle weakness, restrictive cardiomyopathy, and conduction blocks, often presenting in early adulthood
