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Additionally, multiobjective optimization methods such as reinforcement learning 271 and Bayesian optimization 272 can help to create formulations that optimize aerosol performance, mucus penetration and cellular uptake at the same time

S., Suh, Y

2011 Jul;3(3):461-4

Nephro-protective effect of a novel formulation of unopened coconut inflorescence sap powder on gentamicin induced renal damage by modulating oxidative stress and inflammatory markers
