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Disrupting this signaling circuit with the selective inhibitor SP600125 restores mitochondrial membrane potential, curtails keratinocyte hyper proliferation and cytokine release in vitro, and markedly mitigates epidermal hyperkeratosis and inflammation in an imiquimod induced psoriasis model, highlighting JNK inhibition as a promising strategy for redox driven skin pathology

Hospital, Taipei, Taiwan Objective : Detecting vertebral fractures (VFs) is crucial for effective secondary fracture prevention, as they are linked to higher risks of future fractures