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In a micronucleus test on mice, PQQ disodium salt exhibited no genetic toxicity at doses up to 2000 mg/kg of body weight (Nakano et al., 2013)

335 Disruptions in cerebellar-cortical connectivity impair the CNSs ability to modulate motor commands based on sensory feedback, leading to less accurate and less stable joint control

Statins have a proven record of protection from atherosclerotic cardiovascular disease and are extensively used by patients with diabetes [46], hence their potential usefulness in preventing microvascular complications of T2DM has also been tested

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