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Adenyl cyclase

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Reactive gliosis is also characterized by increased glutamate efflux from the astrocytes, which could potentiate excitotoxic cell death of neurons (Sasaki et al, 1997

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Since this requires essentially continuous synthesis and breakdown of PTC, the compounds giving rise to the tCho signal are best understood as part of a dynamic metabolic cycle that includes the membrane-bound choline moieties [69]

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Sjostrand, D., Diamanti, R., Lundgren, C

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