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Long-term safety and efficacy of dimethyl fumarate for up to 13 years in patients with relapsing-remitting multiple sclerosis: final endorse study results

Results There were some suggestive associations for prenatal DAPs with altered activation patterns in both the inferior frontal and inferior parietal lobes of the left hemisphere during a task of cognitive flexibility ( per ten-fold increase in DAPs = 3.37

This downstream spike in LH and FSH may increase Leydig cell testosterone production and spermatogenesis in men with central hypogonadism or functional hormone insufficiency
