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Low folate leads to elevated plasma homocysteine levels [2]
Aging can also affect absorption because the body produces less intrinsic factor, a protein needed for uptake
Another example: individuals with chronic alcoholism often need prolonged thiamine/B-complex support
In comparison to 2-OMe oligonucleotides, the anti-miRNA activity of 2-MOE oligonucleotides, which provide miRNA-based drugs with enhanced nuclease resistance and binding affinity, is significantly superior (Li X et al
