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297,298 The chemical nature of LA oxidation products was studied principally by Gardners group in the 1970s and early 1980s
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While the historical study of dietary antioxidants bears cautionary lessons (51) , in support of a critical antioxidant role for ergothioneine in vivo , the genetic knockout of SLC22A4 in Caenorhabditis elegans increased oxidative damage and reduced lifespan (52)

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