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Morphofunctional characteristics of the glutathione cycle in peripheral blood erythrocytes of pregnant women with a history of cytomegalovirus infection exacerbation during gestation

White blood cells also influence the early differentiation of bone and tendon progenitor cells, and specific PRF protocols can activate white blood cells (especially the monocytes and platelets in the leukocyte-rich matrix) to secrete endogenous growth signaling factors like BMP-2, BMP-7, FGF, VEGF, PDGF, TGF-Beta, and Thrombospondin, which are released locally over the next few days to weeks to accelerate and strengthen tissue repair, and these can further activate recruitment and differentiation of Mesenchymal Stem Cells (MSCs) as well as expression of several tissue remodeling genes

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This hypovolemic state can lead to tissue hypoperfusion, thereby increasing the risk of morbidity and mortality