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10.22270/jddt.v12i2-s.5280 161 RamyaS.LoganathanT.ChandranM.PriyankaR.KavipriyaK.PushpalathaGLGLet al (2022b)
Notably, approaches that aim to reprogram TAMs towards an anti-tumor phenotype, such as by promoting macrophage polarization towards an M1-like phenotype or enhancing macrophage-mediated antigen presentation and T cell activation, hold great potential for cancer immunotherapy
In the anabolic methionine cycle, niacin, in the form of NAD, is a necessary co-factor for the enzymes dihydrofolate reductase in the folate/tetrahydrobiopterin cycle and S-adenosylhomocysteine hydrolase (1)
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