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In the nucleus of hepatocyte, the active form of PKA leads to the activation of transcription factor CREB that links the active site of CRE on PGC-1 gene promoter
S., Levitt, M
Ribulose 5-phosphate Ribose 5-phosphate This is an example of functional group isomerism, where a ketone is converted into an aldehyde
Several kinases can phosphorylate p53 at these sites, including ataxia-telangiectasia mutated (ATM) kinase, ATM- and Rad3-related (ATR) kinase, and checkpoint kinase 1/2(CHK1/2) (Shieh et al., 1997
