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3 5 Whether it maintains a clinically meaningful gastric-emptying delay across months of once-weekly dosing is unproven, and there is a credible mechanistic reason drawn from the broader behavior of long-acting gut-hormone agonists to suspect the effect may attenuate
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Chitin is recognized by TLR2 on the surface of liver immune cells, activating a strong pro-inflammatory response that leads to liver inflammation and damage 104

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