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These beneficial effects depend on senescence being acute and transient, with senescent cells cleared by the immune system, such as macrophages or NK cells, after fulfilling their role [61]

Previously diagnosed with recurrent aphthous ulcers or pemphigus vulgaris, she received unsuccessful treatment with antibiotics and antifungals

In diabetes, NF-B is activated early during the development of DR, and its activity remains elevated even as apoptosis of retinal capillary cells accelerates (91)

Hence, variants such as rs1695 (Ile105Val) affect enzyme activity and have been linked to cancer risk as well as responses to oxidative stress in conditions like Alzheimer's disease