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Subsequently, for these data as well as the alpha diversity analyses, each treatment group (within each phylum or genus for the relative abundance data) was analyzed for normal distribution (ShapiroWilk test) and the data across groups were tested for homoscedasticity (BrownForsythe test)

The Cochrane Database of Systematic Reviews (3) CD004326
Sigma-1 receptors: a new pathway for the modulation of store-operated calcium entry

Tolerance has not been observed in clinical use
