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The final optimization was done via DFT approach with Gaussian 09 software with standard basis set: 6-311G and RB3LYP functional

10.3748/wjg.v24.i48.5462 17 DuzelA.VlainicJ.AntunovicM.MalekinusicD.VrdoljakB.SamaraM.et al (2017)

Additionally, the presence of efflux transporters in the gut lining can actively pump glutathione back into the intestinal lumen, further reducing its absorption

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