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Although they have provided key insight into numerous secondary injury mechanisms and therapy development (1719), there are several limitations to the existing literature: (1) lengthy observation periods of the model organism, (2) high cost for experimentation and associated costs, (3) relatively difficult and lengthy genetic manipulations, and (4) ethical concerns regarding a large number of mammals experiencing pain and debilitating injury
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2023;37(9):e23152DOI
[DOI] [PMC free article] [PubMed] [Google Scholar] Vendrell I, Carrascal M, Vilaro MT, Abian J, Rodriguez-Farre E, Sunol C
