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Michalopoulos, 2010)

1,2 However, the overproduction of ROS can induce cytotoxicity and lead to DNA damage and cell apoptosis

If nausea is severe enough to prevent adequate fluid intake, contact your prescriber immediately rather than waiting for your next appointment

THP-1 cell culture: THP-1 monocytes were seeded at a density of 2 10 5 /ml and differentiated into macrophages in the presence of 100 nM Phorbol-12-myristate-13-acetate (PMA) (Calbiochem, # 524400) for 2 days in RPMI low glucose media in 6-well plates or 4-well chambered slides as described previously 44,165