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Elsevier Academic Press, pp 573584 Dehari-Zeka M, Letaj KR, Selimi QI, Elezaj IR (2020) Blood lead level (BLL), -aminolevulinic acid dehydratase activity (ALAD), hemoglobin (Hb) and hematocrit (hct) in primary school-children and adult residents living in smelter rural areas in Kosovo

Also called sickle cell anemia, SCD is a genetic disease that affects hemoglobin (1), with a specific mutation in the sixth codon of the -globin gene that leads to the substitution of glutamic acid by valine, resulting in the polymerization of red blood cells (2) and causing anemia due to chronic hemolysis of the red blood cells (RBCs)

Indeed, this alcohol metabolite also interacts with DNA and causes damage to the genetic material